Description
5g, 3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic Acid, Na, Prevents the activation of 5-lipoxygenase by binding to 5-lipoxygenase-activating protein (FLAP); however, it does not affect 5-lipoxygenase activity in cell-free systems. Exhibits no effect on other pathways of arachidonic acid metabolism, including the cyclooxygenase, 12-lipoxygenase, and 15-lipoxygenase pathways